RESUMO
A chemiresistive sensor is described for the lung cancer biomarker hexanal. A composite consisting of molecularly imprinted polymer nanoparticles and multiwalled carbon nanotubes was used in the sensor that is typically operated at a voltage of 4 V and is capable of selectively sensing gaseous hexanal at room temperature. It works in the 10 to 200 ppm concentration range and has a 10 ppm detection limit (at S/N = 3). The sensor signal recovers to a value close to its starting value without the need for heating even after exposure to relatively high levels of hexanal. Graphical abstract Schematic presentation of a chemiresistive sensor for detection of hexanal, a cancer biomarker. The hexanal-imprinted polymeric nanoparticles were synthesized, mixed with multiwalled carbon nanotubes and coated on the surface of an interdigitated electrode to produce a nanocomposite chemiresistor gas sensor for hexanal.
Assuntos
Aldeídos/análise , Neoplasias Pulmonares/diagnóstico , Impressão Molecular , Nanotubos de Carbono/química , Polimetil Metacrilato/química , Compostos Orgânicos Voláteis/análise , Biomarcadores Tumorais/análise , Técnicas Biossensoriais , Técnicas Eletroquímicas , Eletrodos , Gases/química , Humanos , Limite de Detecção , Metacrilatos/química , Nanocompostos/química , Nanopartículas/química , Tamanho da Partícula , Polimerização , Propriedades de Superfície , TemperaturaRESUMO
Database URL: http://bioinf.modares.ac.ir/software/cod/.
